Optimization Of Cassava Leaf (Manhihot esculenta Crantz) and Grape Seed Oil (Vitis vinifera L.) Formula Using Simplex Lattice Design Method
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Abstract
The use of natural ingredients in skincare products is increasingly being developed due to their perceived safety and environmental friendliness compared to synthetic chemicals. Cassava leaves (Manihot esculenta Crantz) contain flavonoids, saponins, tannins, and triterpenoids, which function as natural antioxidants. These compounds help protect the skin from free radicals and maintain skin health. Meanwhile, grape seed oil (Vitis vinifera L.) is rich in linoleic acid, which acts as a natural moisturizer and helps maintain the function of the skin’s epidermal barrier. The combination of these two ingredients has the potential to produce high-quality liquid soap. This study aims to optimize the liquid soap formulation using cassava leaf extract and grape seed oil through the Simplex Lattice Design (SLD) method. The research was conducted by designing five formulations with varying concentrations, followed by evaluation based on physical parameters such as organoleptic properties, homogeneity, pH, foam height, viscosity, and formulation stability. The results showed that increasing the concentration of cassava leaf extract raised the viscosity, while grape seed oil tended to reduce foam height. The optimal formula was obtained using Design Expert software with a desirability value of 1.000, and predicted values of pH 8.33, foam height of 147 mm, and viscosity of 663 cPs. Verification results confirmed the agreement between predicted and actual values. It can be concluded that the combination of cassava leaf extract and grape seed oil can produce a stable, high-quality liquid soap formulation that meets physical quality standards
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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
Blume-Peytavi, U., Kottner, J., Sterry, W., Hodin, M. W., Griffiths, T. W., Watson, R. E. B., Hay, R. J., & Griffiths, C. E. M. (2016). Age-Associated Skin Conditions and Diseases: Current Perspectives and Future Options. The Gerontologist, 56(Suppl 2), S230S242.https://doi.org/10.1 093/geront/gnw003
Effendi, A., Silvia, E., Nurmalasari, Y., & Lawren, J. (2020). Hubungan Antara Jenis Kelamin Dengan Angka Kejadian Dermatitis Atopik Di Poliklinik Kulit Dan Kelamin Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Provinsi Lampung Tahun 2019. Jurnal Medika Malahayati, 4(2), 104-111.
Elmitra, E. (2019). Uji sifat fisik formulasi krim tipe A/M dari ekstrak daun singkong (Manihot utilissima). Jurnal Ilmiah Pharmacy, 6(1), 149-157.
Ferdianto R, Riyadi Ph, & Anggo Ad. Minyak Biji Anggur Sebagai Bahan Peminyakan Pada Proses Penyamakan Kulit Ikan Nila (Oreochromis Niloticus) Terhadap Kualitas Fisik. Jurnal Pengolahan Dan Bioteknologi Hasil Perikanan. 2016;5(3):25-31.
Hasim, Falah S, Dewi LK. Pengaruh Perebusan Daun Singkong (Manihot esculenta crantz) terhadap Kadar Total Fenol, Flavonoid dan Aktivitas Antioksidannya. Curr Biochem [Internet]. 2016;3(3):116–27. Available from: http://biokimia.ipb.ac.id
Pramasari, N., Shoviantari, F., & Sholehuddin, S. S. (2024). Formulasi Dan Uji Mutu Fisik Sabun Cair Minyak Biji Anggur (Vitis vinifera L.). Jurnal Pharma Bhakta, 4(1), 43-48.
Rachmadani, A. D., Nurlaila, S. R., & Harismah, K. (2022). Formulasi Dan Uji Stabilitas Sediaan Pembersih Wajah (Cleansing Oil) Berbahan Dasar Minyak Jarak (Ricinus Communis) Formulation And Stability Test For Facial Cleansing (Cleansing Oil) Based On Castor Oil (Ricinus Communis). Journal Farmasi Klinik dan Sains, 2(1), 104-113.
SNI 06-4085-1996. Sabun Mandi .Jakarta. Badan Standarisasi Nasional.
Solikhah, R., Purwantoyo, E., & Rudyatmi, E. (2019). Aktivitas antioksidan dan kadar klorofil kultivar singkong di daerah Wonosobo. Life science, 8(1), 86-95.
Wirawan, W., Tantalu, L., & Suliana, G. (2017). Efektivitas Daun Singkong (Manihot esculenta) Var. Malang 1 Sebagai Pereduksi Kadar Formalin Pada Udang Putih (Pennaeus vannamei). Jurnal Penelitian Pertanian Terapan, 17(3), 170-175.