Paranoid Schizophrenia With Type 2 Diabetes Mellitus And Chronic Suppurative Otitis Media: A Case Report

Authors

  • Muhammad Rizky Huryamin H Universitas Bumigora
  • I Nyoman Ardi Widiatmika Universitas Bumigora
  • Dewi Gotama Universitas Bumigora
  • Devyntya Monica Putri Universitas Bumigora
  • Afiyf Kaysa Waafi Universitas Bumigora
  • Anak Agung Ngurah Bagus Adhitya Wirakusuma Universitas Bumigora
  • Made Bayu Sanjaya Sanjaya Universitas Bumigora

DOI:

https://doi.org/10.36002/js.v5i1.5695

Keywords:

Paranoid schizophrenia, Diabetes mellitus, Otitis Media

Abstract

Schizophrenia is a chronic psychiatric disorder characterized by disturbances in thought processes, perception, emotion, and behavior and is frequently accompanied by medical comorbidities. This case report aimed to describe the clinical manifestations and management of paranoid schizophrenia accompanied by type 2 diabetes mellitus and chronic suppurative otitis media. A descriptive case-report method was applied to a 37-year-old woman. Data were collected through history taking, mental status examination, physical examination, supporting investigations, and review of medical records. Clinical assessment revealed findings consistent with paranoid schizophrenia, accompanied by type 2 diabetes mellitus and chronic suppurative otitis media. These comorbidities increased the complexity of the patient’s condition, requiring comprehensive evaluation of psychiatric symptoms, metabolic control, chronic ear infection, treatment adherence, and potential adverse effects of antipsychotic medication. The patient was managed using an integrated approach involving psychiatric treatment and appropriate management of the accompanying medical conditions. This case highlights the importance of multidisciplinary care, regular clinical monitoring, and continuity of treatment to achieve optimal outcomes in patients with schizophrenia and multiple medical comorbidities.

References

Dong, K., Wang, S., Qu, C., Zheng, K., & Sun, P. (2024). Schizophrenia and type 2 diabetes risk: a systematic review and meta-analysis. Frontiers in Endocrinology, 15, 1395771. https://doi.org/10.3389/fendo.2024.1395771

Fišar, Z. (2022). Biological hypotheses, risk factors, and biomarkers of schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 120, 110626. https://doi.org/10.1016/j.pnpbp.2022.110626

Fleetwood, K. J., Wild, S. H., Licence, K. A., Mercer, S. W., Smith, D. J., & Jackson, C. A. (2023). Severe Mental illness and Type 2 diabetes Outcomes and complications: a Nationwide cohort study. Diabetes Care, 46(7), 1363–1371. https://doi.org/10.2337/dc23-0177

He, Q., Zhu, P., Liu, X., & Huo, C. (2024). Association of new-onset diabetes mellitus in adults with schizophrenia treated with clozapine versus patients treated with olanzapine, risperidone, or quetiapine: A systematic review and meta-analysis. Schizophrenia Research, 271, 371–379. https://doi.org/10.1016/j.schres.2024.07.028

Indrayani, C., Triola, S., Pitra, D. a. H., & Ashan, H. (2023). Otitis media supuratif kronik (OMSK) sebagai penyebab gangguan pendengaran. Scientific Journal, 2(2), 83–95. https://doi.org/10.56260/sciena.v2i2.94

Iqbal, M. S., Zarar, M., Shoaib, A., Hayat, S., Khan, M. H., Amjad, T., Ahmed, H., Azam, N., Asghar, A., & Akram, A. (2026). Living with Chronic Suppurative Otitis Media: Quality of Life Impairments and Psychological Distress. Research Square. https://doi.org/10.21203/rs.3.rs-7786055/v1

Jotic, A. D., Opankovic, A. M., Radin, Z. Z., Cvorovic, L., Vujovic, K. R. S., Krejovic-Trivic, S. B., Bukurov, B. M., Milicic, B. R., & Stojanovic, J. D. (2022). Symptoms of depression, anxiety and stress in patients with chronic otitis media. PLoS ONE, 17(7), e0270793. https://doi.org/10.1371/journal.pone.0270793

Lambert, T., Middleton, T., Chen, R., & Sureshkumar, P. (2023). Prevalence of, and factors associated with, diabetes mellitus in people with severe mental illness attending a multidisciplinary, outpatient cardiometabolic health assessment service. BMJ Open Diabetes Research & Care, 11(1), e003055. https://doi.org/10.1136/bmjdrc-2022-003055

Liu, Y., Liao, Y., & Lin, K. (2024). The relationship between schizophrenia or schizoaffective disorder and type 1 diabetes mellitus: a scoping review of observational studies. Neuropsychiatrie, 38(4), 163–173. https://doi.org/10.1007/s40211-024-00499-y

Luvsannyam, E., Jain, M. S., Pormento, M. K. L., Siddiqui, H., Balagtas, A. R. A., Emuze, B. O., & Poprawski, T. (2022). Neurobiology of Schizophrenia: A Comprehensive Review. Cureus, 14(4), e23959. https://doi.org/10.7759/cureus.23959

McCutcheon, R. A., Keefe, R. S. E., & McGuire, P. K. (2023). Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment. Molecular Psychiatry, 28(5), 1902–1918. https://doi.org/10.1038/s41380-023-01949-9

McCutcheon, R. A., Marques, T. R., & Howes, O. D. (2019). Schizophrenia—An overview. JAMA Psychiatry, 77(2), 201. https://doi.org/10.1001/jamapsychiatry.2019.3360

Rahmadhani, F., Akil, M. A., Sarungallo, F. R., Sulaiman, A. B., & Sanna, A. T. (2024). Karakteristik pasien Otitis media supuratif kronik. FAKUMI MEDICAL JOURNAL Jurnal Mahasiswa Kedokteran, 4(7), 532–538. https://doi.org/10.33096/fmj.v4i7.476

Rantala, M. J., Luoto, S., Borráz-León, J. I., & Krams, I. (2022). Schizophrenia: The new etiological synthesis. Neuroscience & Biobehavioral Reviews, 142, 104894. https://doi.org/10.1016/j.neubiorev.2022.104894

Scheuer, S. H., Kosjerina, V., Lindekilde, N., Pouwer, F., Carstensen, B., Jørgensen, M. E., Benros, M. E., & Andersen, G. S. (2022). Severe mental illness and the risk of diabetes complications: a nationwide, register-based cohort study. The Journal of Clinical Endocrinology & Metabolism, 107(8), e3504–e3514. https://doi.org/10.1210/clinem/dgac204

Zhuo, C., Zhang, Q., Wang, L., Ma, X., Li, R., Ping, J., Zhu, J., Tian, H., & Jiang, D. (2023). Insulin Resistance/Diabetes and Schizophrenia: Potential Shared Genetic Factors and Implications for Better Management of Patients with Schizophrenia. CNS Drugs, 38(1), 33–44. https://doi.org/10.1007/s40263-023-01057-w

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Published

2026-04-13

How to Cite

Muhammad Rizky Huryamin H, Widiatmika, I. N. A., Gotama, D., Putri, D. M., Waafi, A. K., Wirakusuma, A. A. N. B. A., & Sanjaya, M. B. S. (2026). Paranoid Schizophrenia With Type 2 Diabetes Mellitus And Chronic Suppurative Otitis Media: A Case Report. JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI), 5(1), 235–246. https://doi.org/10.36002/js.v5i1.5695

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Vol. 5 No. 1 (2026): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.