Comparison of Ureum Levels before and after Hemodialysis in Kidney Failure Patients at RSD Idaman Banjarbaru

Authors

  • Nadia Universitas Borneo Lestari, Kalimantan Selatan
  • Nurul Amalia Universitas Borneo Lestari, Kalimantan Selatan
  • Bio Putri Ayanti Universitas Borneo Lestari, Kalimantan Selatan

Keywords:

Kidney failure, Hemodialysis, Urea

Abstract

Kidney failure is a disease that causes a decline in kidney function, making the kidneys unable to optimally remove metabolic waste products from the body. As a result, blood urea levels increase. One of the therapies used to help replace kidney function is hemodialysis. Measuring blood urea levels before (pre) and after (post) hemodialysis is necessary to determine the effectiveness of hemodialysis in reducing blood urea levels in patients with kidney failure. This study aimed to determine the comparison of pre- and post-hemodialysis blood urea levels in patients with kidney failure at RSD Idaman Banjarbaru. This study used a descriptive comparative method with a cross-sectional approach. The study sample consisted of 245 patients selected using the total sampling technique. The data used were secondary data obtained from patients’ medical records. Data were analyzed descriptively, followed by the Kolmogorov-Smirnov normality test and the Wilcoxon Signed Rank Test. The results showed that the mean blood urea level before hemodialysis was 130.66 mg/dL, while after hemodialysis it decreased to 45.61 mg/dL. The Wilcoxon test showed an Asymp. Sig. (2-tailed) value of 0.000 (p≤0.05), indicating a significant difference between blood urea levels before and after hemodialysis. Based on the results of the study, it can be concluded that hemodialysis is effective in reducing blood urea levels in patients with kidney failure at RSD Idaman Banjarbaru.

References

Armezya, W., Nasrul, E., & Bahar, E. (2016). Artikel Penelitian Pengaruh Hemodialisis terhadap Urea Reduction Ratio pada Pasien Penyakit Ginjal Kronik Stadium V di RSUP Dr . M . Djamil Padang. Jurnal Kesehatan Andalas, 5(2), 300–305.

Handayani, R., Transyah, C. H., & Aflizarni, R. (2023). Studi Kasus: Terapi Menghisap Es Batu Untuk Mengurangi Rasa Haus Pada Pasien Gagal Ginjal Kronik. Jurnal Kesehatan Medika Saintika, 14, 274–282.

Harun, L. (2024). Analisis Penderita Hipertensi Terhadap Laju Filtrasi Glimerolus ( LFG ) pada Pasien Yang Menjalani Hemodialisis di RS Banjarmasin. Of Nursing Invention, 5(1), 42–52. https://doi.org/https://doi.org/10.33859/jni.v5i1

Kustiyah, S. (2020). Kadar Ureum Sebelum dan Sesudah Hemodialisa pada Pasien Gagal Ginjal Ureum Levels Before and After Hemodialization in Renal Failure Patients. Jurnal Laboratorium Medis, 02(2), 2685–8495. https://ejournal.poltekkes-smg.ac.id/ojs/index.php/JLM/

Kusuma, A. P., Wasdili, F. A. Q., & Mahargyani, W. (2024). Perbandingan Kadar Ureum Pasien Gagal Ginjal Kronik Yang Menjalani Terapi Hemodialisa Di Rs X Tahun 2022. Jurnal Kesehatan Kartika, 19(3), 6631622–6631624. https://doi.org/10.26874/jkkes.v19i3.320

Lulumanin, S., & Fahrurodzi, denny saptono. (2025). Analisis Determinan Penyakit Gagal Ginjal Kronis di Indonesia Berdasarkan Data Survei Kesehatan Indonesia Tahun 2023. Jurnal Ilmiah Rekam Medis Dan Informatika Kesehatan, 15(2), 86–94.

Malfica, M. J., Rosita, L., & Yuantari, R. (2023). Hubungan Ureum dan Kreatinin Serum dengan Lamanya Terapi Hemodialisis pada Pasien Penyakit Ginjal Kronis ( PGK ) di RS PKU Bantul. Berkala Ilmiah Kedokteran Dan Kesehatan Masyarakat, 1(1), 8–18. https://doi.org/10.28885/bikkm.vol1.iss1.art2

Nopriani, Chrisanto, E. Y., & Kusumaningsih, D. (2024). Faktor Yang Berhubungan Dengan Kejadian Gagal Ginjal Kronik Pada Pasien Hemodialisa di RS. Pertamina Bintang Amin Bandar Lampung. Manuju : Malahayati Nursing Journal, 6(5), 2127–2142.

Rahmanti, A., Haksara, E., & Cahyono, A. (2023). Penerapan Aromatherapy Lavender untuk Mengurangi Rumkikt TK II dr . Soedjono Magelang The Application of Lavender Aromatherapy To Reduce Anxiety In Patients Undergoing Hemodialysis At Rumkit TK II. 5(1), 34–44.

Rajagukguk, T., Aritonang, E., & Siahan, M. A. (2021). Analisa Kadar Ureum Pre dan Post Pada Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa Pada Usia Dewasa Yang di Rawat di Rumah Sakit Islam Malahayati Medan. Tekesnos, 3(2).

Sarofah, V. T., Ritonga, A. F., Medis, T. L., & Binawan, U. (2022). Perbandingan Kadar Ureum dan Kreatinin Darah Pasien Gagal Ginjal Kronik Pre dan Post Hemodialisa. Binawan Student Journal, 4(2), 40–44.

Septiani, E., Widyantara, A. B., & Murdiyanto, J. (2025). Gambaran Kadar Ureum dan Kreatinin pada Pasien Gagal Ginjal Kronik Pra dan Post Hemodialisa di RS X Yogyakarta. Jurnal Kesehatan Tambusai, 6(September), 9865–9873.

Sudarso, I., Sulistiyowati, R., Rahaju, M., & Sudarsono, T. A. (2023). Perbandingan Kadar Ureum Sebelum dan Sesudah Hemodialisis pada Penderita Gagal Ginjal Kronik. Jurnal Laboratorium Medis, 05(01), 17–21.

Ullu, A. M. A., ListyawatiNurlina, R., & Wahyuningrum, S. A. (2018). Hubungan Status Nutrisi Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisis di RSUD Prof. DR. W. Z. Johanes. Cendana Medical Journal, 15(4), 425–437.

Xu, Y., Bi, W., Shi, Y., & Liang, X. (2023). Derivation and elimination of uremic toxins from kidney-gut axis. Frontiers in Physiology, August, 1–13. https://doi.org/10.3389/fphys.2023.1123182

Downloads

Published

2026-08-29

How to Cite

Nadia, Amalia, N., & Ayanti, B. P. (2026). Comparison of Ureum Levels before and after Hemodialysis in Kidney Failure Patients at RSD Idaman Banjarbaru. JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI), 5(2), 610–616. Retrieved from https://jurnal.undhirabali.ac.id/index.php/jakasakti/article/view/5803