ANALISIS FITOKONSTITUEN EKSTRAK ETANOL MAKROALGA MERAH (Euchema cottonii) YANG DIKOLEKSI DARI PETANI RUMPUT LAUT DI PULAU SERANGAN, DENPASAR-BALI
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Abstract
Makroalga merah, Euchema cottonii secara tradisional telah dimanfaatkan sebagai makanan fungsional dan kesehatan, seperti menjaga imunitas tubuh dan kesehatan saluran pencernaan. Di sisi lain, makroalga merah ini banyak dimanfaatkan sebagai makanan tradisional pembuatan “rujak bulung” (makanan tradisional khas Bali). Dalam penelitian ini, ekstrak etanol makroalga merah ini dianalisis dan diidentifikasi kandungan senyawa aktifnya. Tujuan dari penelitian ini adalah untuk mengetahui jenis senyawa aktif yang dapat diaplikasikan sebagai sumber obat yang terkandung dalam makroalga merah yang dikoleksi dari petani makroalga merah di Pulau Serangan, Denpasar-Bali. Analisis profil senyawa aktif secara kuantitatif ditentukan dengan menerapkan instrument GC-MS. Hasil penelitian menunjukkan bahwa sebanyak 14 senyawa aktif diperoleh dari ekstrak etanol makroalga merah ini. Hexadecanoic acid, ethyl ester teridentifikasi sebesar 29.81% pada retention time (RT) 15.380. Profil senyawa dengan area peak terendah ditunjukkan oleh Cyclotrisiloxane, hexamethyl yaitu sebesar 0.82% dengan nilai RT sebesar 18.339. Senyawa Hexadecanoic acid dilaporkan memiliki potensi sebagai aktivitas anti-kanker, antimikroba patogen makanan, dan sumber antioksidan.
Kata kunci: Eucheuma cottonii, GCMS, senyawa aktif, Hexadecanoic acid, makanan tradisional
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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
Sani MD, Wiradana PA, Maharani AY, Mawli RE, Mukti AT. The dominance and proportions of plankton in Pacific white shrimp (Litopenaeus vannamei) ponds cultivated with the intensive system in Bulukumba Regency, South Sulawesi, Indonesia. IOP Conf Ser Earth Environ Sci [Internet]. 2022 Jul 1;1036(1):012057. Available from: https://iopscience.iop.org/article/10.1088/1755-1315/1036/1/012057
Rahardjo S, Vauza M, Rukmono D, Wiradana P. Supplementation of hairy eggplant (Solanum ferox) and bitter ginger (Zingiber zerumbet) extracts as phytobiotic agents on whiteleg shrimp (Litopenaeus vannamei). J Adv Vet Anim Res [Internet]. 2022;9(1):78. Available from: https://www.ejmanager.com/fulltextpdf.php?mno=108866
Darli Kyaw Zaw N, Angga Wiradana P, War Naw S, Samuel Nege A, Amin Alamsjah M, Eman Karunia Akbar R, et al. First Report on Molecular Identification of Caulerpa Green Algae from Mandangin Island Indonesia Using Partial 18SrRNA Genes. J Aquac Fish Heal [Internet]. 2020 Aug 28;9(3):252. Available from: https://e-journal.unair.ac.id/JAFH/article/view/19255
Standar Nasional Indonesia. Makroalga merah kering. Jakarta, Indonesia; 2015.
Peñalver R, Lorenzo JM, Ros G, Amarowicz R, Pateiro M, Nieto G. Seaweeds as a Functional Ingredient for a Healthy Diet. Mar Drugs [Internet]. 2020 Jun 5;18(6):301. Available from: https://www.mdpi.com/1660-3397/18/6/301
Sobuj MKA, Islam MA, Islam MS, Islam MM, Mahmud Y, Rafiquzzaman SM. Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh. Sci Rep [Internet]. 2021 Dec 27;11(1):19082. Available from: https://www.nature.com/articles/s41598-021-98461-3
Jönsson M, Allahgholi L, Sardari RRR, Hreggviðsson GO, Nordberg Karlsson E. Extraction and Modification of Macroalgal Polysaccharides for Current and Next-Generation Applications. Molecules [Internet]. 2020 Feb 19;25(4):930. Available from: https://www.mdpi.com/1420-3049/25/4/930
Mokoginta MK, Indriati N, Dharmayanti N, Nurbani SZ. Extraction and characterization of sodium alginates from Sargassum polycystum for manufacturing of tuna (Thunnus sp.) meatballs. IOP Conf Ser Earth Environ Sci [Internet]. 2019 May 1;278(1):012047. Available from: https://iopscience.iop.org/article/10.1088/1755-1315/278/1/012047
Permatasari AAAP, Rosiana IW, Wiradana PA, Lestari MD, Widiastuti NK, Kurniawan SB, et al. Extraction and characterization of sodium alginate from three brown algae collected from Sanur Coastal Waters, Bali as biopolymer agent. Biodiversitas J Biol Divers. 2022;23(3):1655–63.
Prasad Behera D, Vadodariya V, Veeragurunathan V, Sigamani S, Moovendhan M, Srinivasan R, et al. Seaweeds cultivation methods and their role in climate mitigation and environmental cleanup. Total Environ Res Themes [Internet]. 2022 Dec;3–4:100016. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2772809922000168
Akbar, Fitri, Tsania Himayanti, Fakhrina Fathu Rahman, Choirunnisa Basnawi, Nurul Hasrul, et al. Potential extract of red algae (Euchema spinosum) on wound healing: literature review. Makassar Dent J [Internet]. 2022 Aug 31;11(2):148–53. Available from: http://jurnal.pdgimakassar.org/index.php/MDJ/article/view/577
Amaranggana L, Wathoni N. Manfaat Alga Merah (Rhodophyta) Sebagai Sumber Obat dari Bahan Alam. Farmasetika.com (Online) [Internet]. 2017 Aug 7;2(1):16. Available from: http://jurnal.unpad.ac.id/farmasetika/article/view/13203
Cabrita MT, Vale C, Rauter AP. Halogenated Compounds from Marine Algae. Mar Drugs [Internet]. 2010 Aug 9;8(8):2301–17. Available from: http://www.mdpi.com/1660-3397/8/8/2301
Nurjanah N, Ramli RL, Jacoeb AM, Seulalae AV. KARAKTERISTIK FISIKOKIMIA DAN ANTIOKSIDAN KRIM LULUR KOMBINASI BUBUR MAKROALGA MERAH MERAH (Eucheuma cottonii) DAN COKELAT (Sargassum sp.). J Stand [Internet]. 2021 Dec 14;23(3):227. Available from: https://js.bsn.go.id/index.php/standardisasi/article/view/895
Heriyanto H, Kustiningsih I, Sari DK. The effect of temperature and time of extraction on the quality of Semi Refined Carrageenan (SRC). Ma’mun S, Tamura H, Purnomo MRA, editors. MATEC Web Conf [Internet]. 2018 Feb 28;154:01034. Available from: https://www.matec-conferences.org/10.1051/matecconf/201815401034
Sari NKY, Deswiniyanti NW, Wiradana PA. Evaluation of antimicrobial activity and phytochemical screening of red Kamboja (Plumeria rubra L.) extracts. Biog J Ilm Biol [Internet]. 2021 Dec 30;9(2):233–40. Available from: https://journal.uin-alauddin.ac.id/index.php/biogenesis/article/view/25409
Astiti NPA, Ramona Y. GC-MS Analysis of Active and Applicable Compounds in Methanol Extract of Sweet Star Fruit (Averrhoa carambola L.) Leaves. HAYATI J Biosci [Internet]. 2021 Jan 1;28(1):12. Available from: https://journal.ipb.ac.id/index.php/hayati/article/view/35298
Watiniasih NL, Budiarsa IN, Antara ING, Wiradana PA. Propolis extract as a green bacterial corrosion inhibitor on three types of metals. Biodiversitas J Biol Divers [Internet]. 2022 Sep 23;23(9). Available from: https://smujo.id/biodiv/article/view/11763
Zhang Q-W, Lin L-G, Ye W-C. Techniques for extraction and isolation of natural products: a comprehensive review. Chin Med [Internet]. 2018 Dec 17;13(1):20. Available from: https://cmjournal.biomedcentral.com/articles/10.1186/s13020-018-0177-x
Bharath B, Perinbam K, Devanesan S, AlSalhi MS, Saravanan M. Evaluation of the anticancer potential of Hexadecanoic acid from brown algae Turbinaria ornata on HT–29 colon cancer cells. J Mol Struct [Internet]. 2021 Jul;1235:130229. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0022286021003604
Perumal P, Dhanasundaram S, Aravinth A, Amutha V, Santhanam P. Larvicidal property of the extracts of the seaweeds; Sargassum wightii, S. ilicifolium and Gelidiella acerosa against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus. Biocatal Agric Biotechnol [Internet]. 2022 Aug;43:102436. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1878818122001633
Net-anong S, Prommee N, Dechayont B, Prajuabjinda O, Yangthaworn K, Chunthorng-Orn J, et al. Calamus caesius (Rattan) wood: Chemical constituents, biological activities’ relative medicinal properties from Thai medicinal scriptures, and in silico antioxidant activity. Arab J Chem [Internet]. 2023 Aug;16(8):104990. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1878535223004525
Hussain I, Gour NK, Deka RC. Kinetics and thermochemistry of hydrolysis mechanism of a novel anticancer agent trans-[PtCl2(dimethylamine)(isopropylamine)]: A DFT study. Chem Phys Lett [Internet]. 2016 May;651:216–20. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0009261416301506
Inés Molina RD, Campos-Silva R, Díaz MA, Macedo AJ, Blázquez MA, Alberto MR, et al. Inhibition of bacterial virulence factors of foodborne pathogens by paprika (Capsicum annuum L.) extracts. Food Control [Internet]. 2022 Mar;133:108568. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0956713521007064
Dobhal P, Agnihotri S, Ashfaqullah S, Tamta S. Effect of salicylic acid elicitor on antioxidant potential and chemical composition of in vitro raised plants of Berberis asiatica Roxb. ex DC. Nat Prod Res [Internet]. 2022 Nov 3;1–8. Available from: https://www.tandfonline.com/doi/full/10.1080/14786419.2022.2141737
Salini R, Santhakumari S, Veera Ravi A, Karutha Pandian S. Synergistic antibiofilm efficacy of undecanoic acid and auxins against quorum sensing mediated biofilm formation of luminescent Vibrio harveyi. Aquaculture [Internet]. 2019 Jan;498:162–70. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0044848617321713
Charan Raja MR, Kar A, Srinivasan S, Chellappan D, Debnath J, Kar Mahapatra S. Oral administration of eugenol oleate cures experimental visceral leishmaniasis through cytokines abundance. Cytokine [Internet]. 2021 Sep;145:155301. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1043466620303173
Karmakar E, Das P, Yatham P, Kumar D, Mukhopadhyay S, Roy SS. Seedpod extracts of Wrightia tinctoria shows significant anti-inflammatory effects in HepG2 and RAW-264.7cell lines. Nat Prod Res [Internet]. 2022 Nov 17;1–5. Available from: https://www.tandfonline.com/doi/full/10.1080/14786419.2022.2146688